Cialis Canada

A selective inhibitor of cyclic guanosine monophosphate  (cGMP) – specific phosphodiesterase type 5 – tadalafil has the following structural formula:

Tadafil is a crystalline substance insoluble in water and practically insoluble in ethanol. Tadalafil is chemically designed as pyrazino[1,2:1.6]pyrido[3.4-b]indole-1.4-dione, 6-(1.3-benzodioxol – 5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-.

Cialis is produced in form of tablets containing tadalafil in 2.5, 5, 10 and 20 mg. The other inactive components of the drug are: croscarmellose sodium, hydroxypropyl cellulose, hypromellose, iron oxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate, titanium dioxide, talc and triacetin. If you have allergy to any component of the drug, you should consult your doctor to define the possible risk of allergic reactions.

The drug should be taken exactly as prescribed by your doctor. Follow all your doctor’s instructions, for more information you can also read directions on your prescription label.

Do not exceed the prescribed dose, if you think your dose is not effective for you, first consult your doctor. Take the drug with or without food.

Cialis is taken when needed, just before sexual activity and may be taken daily regardless of the time of sexual activity.  Cialis for daily use is taken in lower doses.  Do not take Cialis more than once a day.

Contact your doctor or seek emergency medical attention if you experience any side effects of the drug, especially if your erection is painful and prolonged (4-6 hours).

The drug will help you to achieve an erection only in case sexual stimulation occurs. An erection will not occur if there is a sexual stimulation. For more details consult your doctor.

It is important to remember that Cialis  can interact with other medicines. Before taking the drug, inform your doctor about all prescriptions you have. Do not take the drug with Viagra, Levitra, Kamagra or other medications for ED.

Before taking tadalafil you should consult your doctor in order to avoid possible side effects and have the right dose for you.  It is important to tell your doctor about all the health disorders you have been previously diagnosed. Your doctor may recommend starting with a smaller dose and if you have good (bad) tolerance to the drug, the dose can be increased (decreased).

Your doctor may recommend a Cialis dose adjustment or special tests if you have some of the following health conditions in order to eliminate side effects and direct you the exact dose:

• heart disease or problems with heart rhythm;
• a recent heart attack (within the past 3month);
• a recent history (within the past 6 months) of stroke or congestive heart failure;
• chest pain;
• high or low blood pressure;
• liver disease or kidney disease;
• as sickle cell anemia or leukemia;
• hemophilia;
• a stomach ulcer;
• a physical deformity of the penis (such as Peyronie’s disease) and some others.

You should tell your doctor about allergic reactions you have had before and in case you have allergy to tadalafil or other components of Cialis.

FDA placed Cialis to the pregnancy category B.  That means that Cialis is not expected to harm an unborn baby. Still it is necessary to inform your doctor if you are pregnant or plan to become pregnant during treatment. It is also important to tell your doctor if you are breast-feeding a baby before taking tadalafil.

Follow all your doctor’s prescriptions and ask him any questions you have about the drug.

Normal erection is a reflex caused by increased penile blood flow during sexual stimulation. The sexual response is a result of relaxation of penile arteries and corpus cavernosal smooth muscles due to the release of nitric oxide (NO). the inhibition of phosphodiesterase type 5 (PDE 5) makes erectile function better by enlarging the cGMP (cyclic Guanosine Monophosphate) which relaxes smoothe muscles tissues. In blood vessels relaxation of vascular smooth muscles lead to vasodilation and increased blood flow. The main component of Cialis tadalafil inhibits PDE 5 and improves erectile function by increasing the cGMP. Still the effect will be min if there is no sexual stimulation. Sexual stimulation is necessary to release nitric oxide.

Clinical studies have confirmed that a selective inhibitor of PDE5 is found in corpus cavernosum smooth muscle, vascular and visceral smooth muscle, kidney, lung, and pancreas. The same studies proved that the effect of tadalafil is more potent on PDE5 than on other phosphodiesterases.

Cialis relaxes muscles and increases blood flow to particular areas of the body. The effect of the drug appears in 30 minutes after taking and lasts for about 36 hours. A male taking  Cialis for the first time should consider the dose prescribed very carefully. An overdose of Cialis is possible if a person does not follow the prescribed dose and takes much of this drug.

It is vital to know some things before taking Cialis. Read this information about the drug carefully and ask your doctor if you have any questions about Cialis.

Do not take Cialis if you are allergic to tadalafil, or to any of the drug’s component.

Do not take Cialis if you use a nitrate drug for chest pain treatment or for heart problems. These medicines include: nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, Minitran, Deponit, Transderm-Nitro), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket), or amyl nitrate or nitrite. Nitrate drugs with Cialis can cause a decrease in blood pressure, which can result in fainting, stroke, or heart attack.

While taking this drug, be attentive to any changes in your health condition such as: dizziness during sexual activity, or pain, numbness, or tingling in your chest, arms, neck, or jaw. If you have these conditions you should stop and call your doctor immediately. You could experience a serious side effect of this drug.

Cialis should be taken once a day with 24 hours interval between doses to avoid overdose and possible side effects. In case you have prolonged (more than 4 hours) and painful erection, call your doctor immediately; prolonged erection (priapism) can damage the penis and result in impotence.

Cialis may lessen blood flow to the optic nerve of the eye, causing sudden vision loss. Especially vulnerable to this side effect are people with heart diseases, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. However, it is not proved that Cialis causes vision loss. In case of sudden vision loss stop using the drug and get emergency medical help.

Cialis can be used as needed or daily for the treatment of erectile dysfunction.

For use as needed Cialis starting dose for most patients is 10mg, it can vary due to health conditions of the patient and his response to therapy. The dose may be increased to 20mg in case of good health conditions and response to the drug. The dose may be decreased to 5mg in case of worse tolerability to the drug and individual health conditions. The drug should be taken once in 24 hours.

When taken as needed Cialis improves erectile function in comparison to placebo up to 36 hours. If you think you take too much of the drug, call your doctor. Overdose symptoms may include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.

For daily use Cialis starting dose is 2.5mg, it can be increase to 5mg in case of good response to the therapy. The drug should be taken at the same time daily in case of missing dose, the next dose is taken.

Cialis may be taken with or without food.

Cialis is produced in a form of film coated almond shaped tablets in different shades of yellow:

2.5mg tablets with C2 ½

5mg tablets with C 5

10mg tablets with C10

20mg tablets with C20

Generic Name: Tadalafil

Brand Name: Cialis

Cialis (active component – Tadalafil) is a PDEF5 inhibitor used to treat erectile dysfunction (impotence) in men by relaxing muscles and increasing blood flow to the penis.

Cialis is manufactured by Eli Lilly and Company in a form of tablets, in 5 mg, 10 mg, and 20 mg doses. The drug received Food and Drug Administration (FDA) approval in 2003 after undergoing a variety of clinical trials.

Tadalafil pills are produced under two brand names – Cialis and Adcirca.  Cialis relaxes muscles and increases blood flow to penis and treat erectile dysfunction in men. Adrica is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

Cialis should not be combined with other PDE5 inhibitors including Adrica or erectile dysfunction therapies.

Man’s inability to get and maintain an erection for long enough to have sex is called importance or erectile dysfunction. Cialis is a breakthrough medicine for treatment mild and serious erectile dysfunction in men, showing good results in the beginning of the treatment.

The drug acts by increasing blood inflow into the penis while there is a sexual stimulation. It helps a male to achieve and maintain an erection.

Cialis is rapidly absorbed in the human body with the effect within half an hour after taking it. The effect lasts up to 36 hours.

The dose for the treatment of importance in man is observed and prescribed by the doctor. Before taking this drug you should consult the doctor. The dose can be prescribed for use as needed and for everyday use. Follow all the doctor’s directions to avoid side effects and possible health risks. An overdose of the drug can occur if a person takes a larger dose.

Ask your doctor any questions about Cialis, especially if you are taking other drugs or have certain health conditions. Cialis is to be taken only by the patient for whom it is prescribed.

Cialis can be taken with or without food. The drug is stored at room temperature away from moisture, heat and light. Store this medication out of the reach of children.